The Drug Discovery Division of our partner is currently looking for an Associate Principal Scientist to join their team and support their development program. This position offers an opportunity to work for a company that is operating in a critical sector of the economy and has a strong and exciting future.

The successful candidate will have a background in a relevant scientific discipline such as pharmacology or pharmaceutical sciences and experience working on DMPK drug discovery and/or development projects. Working knowledge of multiple DMPK/ADME assays as well as experience in applying DMPK science to small molecule drug discovery/development projects will also be required.

Our partner is a dynamic, fast-growing organisation, with an enviable reputation for leading-edge science, offering contract research services to some of the world’s leading pharmaceutical companies, and solving what were believed to be unsolvable scientific challenges. Their team of experts believes in their ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for their clients, and always operating ethically and with integrity. They take pride in their professionalism and commitment to always deliver their very best work.

Responsibilities:

• Provide technical direction and apply innovation to problem-solving in projects across the Drug Discovery organisation within own area of expertise.
• Conduct human PK, dose predictions and using routine approaches and including PBPK as appropriate using available software.
• Collate and interpret results from the PK and ADME teams within the organisation and further analyse/model/simulate in the context of the project aims. 
• Ensure the smooth operation and scheduling of the DMPK screening strategy for the matrix drug discovery teams internal to PDDSE and external with clients.
• Maintenance and presentation of IVIVE and SAR for ADME properties to a high standard.
• Provide quality data, written reports and presentations internally and to our partners to ensure regular progress updates and client satisfaction.
• Able to act as a point of contact and manage client interactions for specified parts of an integrated project.
• The role requires meticulous attention to detail and for all work to be conducted strictly in accordance with company Policies and Procedures and Standard Operating Procedures.

Requirements:

• BSc or higher in relevant scientific discipline, pharmacology, pharmaceutical sciences.
• Experience working in DMPK drug discovery and/or development projects with an appreciation of related disciplines.
• Working knowledge of multiple DMPK/ADME assays.
• Experience in applying DMPK science to small molecule drug discovery/development projects.

What will you get:

• A competitive salary and a progressive and comprehensive suite of employee benefits.
• A state-of-the-art working environment on site.
• An exciting opportunity for growth and development.
• Support for funding for relevant training and development programmes.